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Biotech / Medical : Biotech & Pharma.T.A,

BIB 75.40

+5.5%

Nov 11 4:00 PM EST

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To: Biomaven who wrote (684)	2/27/2006 1:21:20 PM
From: Jibacoa	Read Replies (1) of 3722

In its recent letter to the shareholders, RGEN's CEO Walter Herlihy makes reference to the patent concerning CTLA4-Ig for RA, which is the one that Peter mentioned on his note of Jan.25 last year. According to W.H., the FDA approved BMY's application for Orencia for RA treatment in December and in January RGEN & Michigan Univ. filed a complaint for infringement of US Patent No.6,685,941 which covers methods for using CTLA4-Ig for treating RA. He said that RGEN is seeking a royalty licensing agreement with BMY either by "litigation or negotiation".<g> They also have a claim pending against IMCL since Damon Biotech, a predecessor of RGEN had developed a cell line that contained their patented technology for the NCI to produce the monoclonal antibody wich IMCL now produces as Erbitux for treatment of colorectal Ca. Oral arguments for summary judgement on that claim were already held in February. RGEN Needs to close above 4.20 before it can test the resistance aove 4.45 and then the Feb.6 H at 5.08 <g> bigcharts.marketwatch.com RGEN had $23.076M in cash as of Dec.31 and expects to close the fiscal year ending next month about "breakeven" (with gross profits around $9M after total revenues of $12.5M ) It seems that RGEN has a good chance of reaching the $8 level in the next year and the R/R looks favorable, so I think that I will increase my position a little.<g> bigcharts.marketwatch.com Bernard

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