XOMA. Bull or Bear? Message Board

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Biotech / Medical : XOMA. Bull or Bear?

XOMA 26.20

+3.5%

Dec 30 3:59 PM EST

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To: Turbo Lawyer who wrote (3830)	9/18/1997 8:03:00 PM
From: Andrew H	of 17367

TL, don't think we can extrapolate since the P factor to stop the trial was built into the LGND trial protocol. Unless someone knows the Xoma trial protocol. Also the LGND trial was not an FDA trial. However, if the previous figures of only 1 death out of 25 is any indication, then because of the particularly nasty nature of meningococcemia and the fact that it targets children, I think there is a possiblity that the FDA will halt the trials. Also somewhere we heard the figure of only 5 or 6 deaths total (in both treatment and placebo groups) of 60 some. On the the other hand, FDA knows that once this drug is on the market, doctors will prescribe it off label for a wide variety of indications and that may be a tempering factor. Also, as Robert mentions, the sample size is pretty small and that may confound the p factor. I think we will just have to wait and see.

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