Indications -- Psoriasis/Chronic Inflammation Message Board

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Biotech / Medical : Indications -- Psoriasis/Chronic Inflammation

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To: keokalani'nui who wrote (534)	3/15/2006 7:23:46 PM
From: software salesperson	Read Replies (1) of 631

Treatments in development for psoriasis and/or psoriatic arthritis First created November 2001, updated December 2005 Name Company Delivery Mechanism Mechanism of Action Phase Indication Alefacept (Amevive) Biogen Idec injectable T-cell modulator II psoriatic arthritis ABT874 Abbott Immunology injectable IL-12/ IL-23 inhibitor II psoriasis AS210 (Psoraxine) Astralis, Ltd. injectable anti-inflammatory agent II psoriasis CC-10004 Celgene oral TNF-alpha inhibitor II psoriasis CGC1072 (PsorBan) Cellgate, Inc. topical anti-inflammatory agent II psoriasis CNTO 1275 Centocor, Inc. injectable IL-12/ IL-23 inhibitor II psoriasis CRx-140 CombinatoRx oral anti-inflammatory agent II psoriasis IC747 Icos Corp. oral LFA-1 inhibitor II psoriasis MM-093 Merrimack Pharmaceuticals oral anti-inflammatory agent II psoriasis Paclitaxel (Paxceed) Angiotech Pharmaceuticals oral cell-growth inhibitor II psoriasis PhotoPoint MV9411 Miravant Medical Technologies oral with light photodynamic therapy for plaque psoriasis II psoriasis Pimecrolimus/ ASM981 (Elidel) Novartis Pharmaceuticals Corp. oral T-cell and mast-cell inhibitor II psoriasis QRX-101(becocalcidiol) QuatRx Pharmaceuticals Co. topical vitamin D analog II psoriasis Rambazole Barrier Therapeutics oral retinoid II psoriasis Rambazole Barrier Therapeutics topical retinoid II psoriasis STA-5326 Synta Pharmaceuticals oral IL-12/ IL-23 inhibitor II psoriasis Targretin Ligand Pharmaceuticals topical retinoid II psoriasis VX-765 Vertex Pharmaceuticals oral anti-inflammatory agent II psoriasis Adalimumab (Humira) Abbott Immunology injectable TNF-alpha inhibitor III psoriasis BG-12 Biogen Idec oral fumaric acid ester III psoriasis Infliximab (Remicade) Centocor, Inc. injectable TNF-alpha inhibitor III psoriasis ISA 247 Isotechnika oral anti-inflammatory agent III psoriasis Rosiglitazone maleate (Avandia) GlaxoSmithKline oral anti-diabetic agent III psoriasis Recent approvals Adalimumab (Humira) Abbott Immunology injectable TNF-alpha inhibitor approved psoriatic arthritis Clobetasol propionate (Clobex spray) Galderma topical steroid approved psoriasis Infliximab (Remicade) Centocor, Inc. Centocor, Inc. injectable TNF-alpha inhibitor approved psoriatic arthritis Calcipotriene/beta- methasone dipropionate (Taclonex) Warner Chilcott topical anti-inflammatory and cell growth inhibitor approved (available spring 2006) psoriasis

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