(company is private I think, so nothing from an investment perspective).
What is the best way to start research/get a handle on a co. at this phase to decide if worth it?..I'll cross post this to the BVF thread in case you don't have the time/inclination today..
ptcbio.com
PTC THERAPEUTICS FILES FOR INITIAL PUBLIC OFFERING
SOUTH PLAINFIELD, N.J., March 31, 2006 - PTC Therapeutics, Inc. today announced that the company has filed with the Securities and Exchange Commission a registration statement relating to the proposed initial public offering of shares of its common stock. All shares of the common stock to be sold in the offering will be sold by PTC Therapeutics, Inc.
Morgan Stanley & Co. Incorporated will act as sole book-runner and lead manager, J.P. Morgan Securities Inc. will act as co-lead manager and Pacific Growth Equities, LLC will act as co-manager in the offering.
A registration statement relating to these securities has been filed with the Securities and Exchange Commission but has not yet become effective. These securities may not be sold nor may offers to buy be accepted prior to the time the registration statement becomes effective. When available, a preliminary prospectus may be obtained from Morgan Stanley & Co. Incorporated, by emailing prospectus@morganstanley.com, or by contacting the prospectus department at Morgan Stanley & Co. Incorporated, 1585 Broadway, New York, New York 10036, by telephone at 212-761-6775.
ABOUT PTC124
PTC124 is an orally delivered investigational product candidate in development for the treatment of genetic disorders due to nonsense mutations. Nonsense mutations are single-point alterations in the genetic code that prematurely halt the translation process, producing a shortened, non-functional protein. In pre-clinical trials, the administration of PTC124 allowed the restoration of the production of full-length, functional proteins. PTC124 has demonstrated activity in preclinical genetic disease models harboring nonsense mutations. In Phase 1 clinical trials, PTC124 was generally well tolerated, achieved target plasma concentrations that have been associated with activity in preclinical models, and did not induce ribosomal readthrough of normal stop codons. Pharmacokinetic modeling of the Phase 1 results allowed development of a dosing regimen for the Phase 2 studies in cystic fibrosis (CF) and Duchenne muscular dystrophy (DMD). It is estimated that 10% of the cases of CF and 15% of the cases of DMD are due to nonsense mutations. PTC believes that PTC124 is potentially applicable to a broad range of other genetic disorders in which a nonsense mutation is the cause of the disease. The FDA has granted PTC124 Fast-Track designation and Orphan Drug
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development of and market for drugs that treat hepatitis C. Forward-looking statements relate to expectations or forecasts of future events. Schering-Plough does not assume the obligation to update any forward-looking statement. Many factors could cause actual results to differ materially from Schering-Plough’s forward-looking statements, including market forces, economic factors, product availability, patent and other intellectual property protection, current and future branded, generic or over-the-counter competition, the regulatory process, and any developments following regulatory approval, among other uncertainties. For further details about these and other factors that may impact the forward-looking statements, see Schering-Plough’s Securities and Exchange Commission filings, including Item 1A. Risk Factors in the Company’s 2005 10-K.
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ABOUT PTC THERAPEUTICS, INC.
PTC is a biopharmaceutical company focused on the discovery, development, and commercialization of orally administered, proprietary small-molecule drugs that target post-transcriptional control processes. Post-transcriptional control processes regulate the rate and timing of protein production and are of central importance to proper cellular function. PTC has assembled proprietary technologies and extensive knowledge of post-transcriptional control processes that it applies in its drug discovery and development activities. PTC’s current pipeline of clinical and preclinical product candidates addresses multiple indications, including genetic disorders, oncology, and infectious diseases.
CONTACT:
Jane Baj
PTC Therapeutics, Inc.
(908) 222-7000, x167
jbaj@ptcbio.com |
