I don't know if I support it for a few reasons. For one, vitamin C is not protective against scurvy. Pauling should have know that from studying the work of Szent-Gyorgy another Nobel winner whose work on the bioflavonoids in 1928 proved that C alone cannot affect scurvy, but raw limes with little C per serving, perhaps 25 mgs, could. The secret was in the trace elements that were anti-oxidant. Although modern literature credits the bioflavonoids as a recent discovery, saying that only lately have the effects of substances like phytosterol, polyphenol and pro-xanthcyanidin been found, in fact Szent-Gyrogy clearly demonstrated their therapeutic use in the 20's. Paulings references seem to indicate he is ignorant of this important fact.
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This does not negate the research, as Pauling conducted many tests. But it does underscore that perhaps more research is needed. Orange juice and Apple juice have powers to reduce cholesterol markedly, and their main pharmacologically active components appear to be rutin, pectin, hesperidin, and quercetin. Without these substances vitamin C is much less effective. I think one would be far more advised to overdose on citrus fruit rather than pop C pills, as a means of repairing your circulatory system. If one was prone to bleeding stroke I would become fast friends with citrus fruits. The strengthening effect they have on the peripheral vascular system may be what the MD ordered.
# The bioflavonoids are helpful in the absorption of vitamin C and protect the multifunctional vitamin C molecule from destruction, thereby improving and prolonging its functioning. They are therefore indirectly, and possibly directly, involved in maintaining the health of collagen. Collagen holds all the tissues of the body together - it is a major component of bone, teeth and scar tissue formed during wound healing and bone fractures.
# The collagen repair and anti-inflammatory action of bioflavonoids may also help joint and connective tissue problems like tendonitis, arthritis, rheumatoid arthritis, injury, fibromyalgia and gout.
# Their main known function is to increase the strength of the capillaries. In fact, the letter P, for permeability factor, was initially given to this group of nutrients because of their role in improving the capillary lining's permeability and integrity - that is, the passage of oxygen, carbon dioxide, and nutrients through capillary walls. The capillaries link the arteries to the veins - they deliver oxygen and nutrients to the organs, tissues, and cells and then pick up carbon dioxide and wastes and carry them through the veins and back to the heart. By their support of the capillaries, bioflavonoids help to prevent haemorrhage and rupture of these tiny vessels, which could lead to easy bruising.
# A high bioflavonoid intake has also been linked to a lower risk of heart attack, although further investigation in this area is warranted.
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