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Biotech / Medical : XOMA. Bull or Bear?
XOMA 26.06+0.3%Dec 26 9:30 AM EST

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To: aknahow who wrote (3884)9/24/1997 3:39:00 AM
From: Webhead   of 17367
 
Actually, I think that this is a phase I study (though i'm sure that they'll build a little efficacy testing into it so it may be more a phase I/II). It's unlikely that there will be much of a safety problem given the large number of people who have recieved BPI. However, because some CF patients have antibodies directed against BPI it will be important to determine the pharmokinetics in patients +/- BPI antibodiess to nail down the actual indication. It's also possible that patients with BPI antibodies might react to BPI injections unfavorably so safety might be a non-trivial concern.

just my 0.02

Ed
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