Genaissance Pharmaceuticals (GNSC) Message Board

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Biotech / Medical : Genaissance Pharmaceuticals (GNSC)

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To: Mike McFarland who wrote (182)	7/27/2006 12:57:01 PM
From: Jim Oravetz	of 183

Posted in CLDA thread: Message 22663025 "Going forward, a key objective is to optimize vilazodone, a promising asset obtained through our acquisition of Genaissance. Vilazodone is a dual action, SSRI/5HT1A partial agonist drug candidate for depression with unique pharmacological properties, including an anti-anxiety component that has recently entered into a pivotal Phase III clinical study. We are now in the patient enrollment stage of the Phase III study, and we are very excited about the potential for this drug candidate. In addition, using the genomics expertise of our Cogenics(TM) and PGxHealth(TM) divisions, we are examining certain critical genetic biomarkers that may enable us to develop a genetic test to better target patient populations for vilazodone. This potential-associated genetic test capability is at the cutting edge of an important facet of personalized medicine that is gaining the attention of the medical community and regulators. After significant review, management collectively determined that the vilazodone asset warrants an environment where it can thrive and where it can be funded in a way that optimizes the likelihood for success. Consequently, we are moving ahead with plans to spin this asset off to shareholders through the creation and financing of a new company called Precigen Therapeutics, Inc. We are working to complete this effort as soon as possible.

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