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Biotech / Medical : Infinity Pharmaceuticals
INFI 0.0160-4.8%Sep 29 5:00 PM EST

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To: Mike McFarland who wrote (53)7/27/2006 5:03:16 PM
From: tuck  Read Replies (1) of 210
 
>>You wonder if Kosan will walk away from their
17-aag, fall back to their epothilone program.

Holtzman says they have a better drug, and I
have to believe it, well I don't have to, but
I want to. The bit about solubility rings true
and sounds very plausible, to me. <<

Kosan might walk away from 17-AAG (though I think some of the studies are funded by NIH, so why not keep it and learn?), but probably not 17-DMAG. 17-DMAG is the 2nd generation compound, and is hydrophilic. Addresses the solubility issues that Infinity crows about solving. Couldn't tell you which is the better drug.

Message 22663965

Cheers, Tuck
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