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Biotech / Medical : Biotech Valuation
CRSP 55.26+1.2%Nov 11 3:59 PM EST
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To: NeuroInvestment who wrote (20660)7/27/2006 11:46:31 PM
From: dr.praveen  Read Replies (2) of 52153
 
Paion

Hi Harry,

What do you think of paion?

Their latest presentation

wsw.com

This is from an old post of mine:

I like Paion for the foll reasons:

1) Low market cap of approx 350 Mil

2) good management( Family )

3) Desmoteplase(plasminogen activator) and Enecadin(neuroprotectant) combination which is reco by intl stroke experts. Smart choice which RNVS doesn't have.

3) Pipeline also consists of Solulin(If successful?) which is a thrombin inhibitor used to treat CVS/stroke.

Solulin acts only from the moment thrombin is formed and could therefore deliver a much more targeted effect than other products.

4)About the lead drug desmoteplase, A plasminogen activator derived from the saliva of the vampire bat Desmodus rotundus with approx. 70% structural homology to t-PA

5)Administration time after 3–9h Stroke onset,which is a good time period to administer in the pt and in bolus.

6) Good fibrin selectivity which decreases risk of bleeding and faster action

7)Safe in elderly pts

8)Elimination half life from 2-4.7 hrs which is a good period to prevent reocclusion.

9)Clinical outcome, reperfusion, Volume change of the infarct are very good and dose dependant which shows that the drug is effective.

10)Good partnership's for Desmoteplase with FRX in US and Lundbeck for rest of the world.(Royalty rates are not disclosed)

Thanks,
Praveen
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