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Biotech / Medical : Biotech Valuation

CRSP 53.47

+0.3%

Nov 28 9:30 AM EST

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To: EdR who wrote (20702)	7/31/2006 9:39:36 PM
From: zeta1961	Read Replies (1) of 52153

Ed, I too am sorry to hear about the mets..I despise cancer..I'd recently been thinking about you when my sister finished her last bag of 5fu.. There are studies being done with radiosensitizers but their coupled with radiation.. Myriad(disclosure, I have a position) has a Phase 1 study with a molecule called MPC-6827 or Azixa..Rick is much better versed in this one but quickly: it's chemo and not radiation; according to preclinicals, it has much greater blood brain barrier penetration which as ýou know is the crucial issue with treating brain lesions..Last I heard(January JPMorgan), they'd not reached the MTD yet..The docs at M.D. Anderson and NY-Cornell are enrolling patients..if I had to make your decision or advise, this first place I'd explore..I'd want to know they'd advanced the dosing.. It is a program that I have been excited about watching mature..yet I have no idea how the patients dosed so far are doing regards efficacy(except in January, no grade 3 SAE's)..perhaps Rick and others over at the Myriad thread have more up-to-date information.. I'll do some more digging and pass it on.. Elisabeth

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