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Biotech / Medical : Theravance - THRX
THRX 9.810+0.4%Jan 8 4:00 PM EST

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To: DewDiligence_on_SI who wrote (39)8/28/2006 10:22:51 AM
From: Biomaven  Read Replies (2) of 74
 
hitting on superiority while missing on non-inferiority is rare, but it can happen

Could you give an example?

See the abstract on this issue I posted on the valuation thread.

Further, your two-bites analysis would presumably imply a .025 level for the non-inferiority trial as well, but there is no mention of that.

I do grant that .025 is suggestive of a two-bite analysis - I just don't understand why.

These two presentations are interesting:

findarticles.com

amstat.org

Peter
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