The Serenex slide I pointed to awhile back has something
about elevated rat liver enzymes, diarrhea, and
thrombocytopenia (what the devil is that) for 17dmag, fwiw.
Maybe Infinity's competition is Serenex?
(and Kosan, Astex, Synta, Arqule, Neutec, Vernalis)
Are you caffeinated this evening Tuck, I can't keep
up with you. It is no wonder I had to give up
trading. But this buy and hold approach is for the dogs <g>
<googling "Nereus polyketide" and "Kosan polyketide" and behold the difference>
The best I can do is point to the article I posted on
the Nereus thread. So yeah, I guess I am reaching.
"bryostatin isolated from the bryozoan Bugula neritina, does
not superficially resemble any microbial product, it is a
complex polyketide. Complex polyketides (non-aromatic
macrolides) are typically produced by bacteria and fungi,
and hence, it was suggested that bryostatin is produced by a
microbial symbiont of the bryozoan" |
