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Biotech / Medical : Infinity Pharmaceuticals
INFI 0.0160-4.8%Sep 29 5:00 PM EST

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To: Mike McFarland who wrote (61)8/30/2006 3:20:03 PM
From: nigel bates  Read Replies (2) of 210
 
>>Vernalis plc
vernalis.com
the real thing, there's probably a thread and I just never stumbled onto it<<

Don't think so, but it will be interesting to see if we hear anything about the Novartis/Vernalis compound this year, since Novartis bought Neutec -

In December 2003, Vernalis formed a research collaboration with the Novartis Institutes for BioMedical Research, Inc., (Novartis) to investigate inhibitors of Hsp90. After an initial six-month evaluation period, Novartis exercised its option to license exclusive worldwide rights to Vernalis’ Hsp90 programme. The companies are conducting a joint research programme under which Novartis provides research funding to Vernalis for an initial three-year period. In addition, Novartis is responsible for funding and conducting the development of product candidates as well as for commercialisation.

In December 2005, Vernalis announced that Novartis had selected a preclinical development candidate and compound is expected to enter clinical development in H2 2006...


Particularly since Novartis bought Neutec. I was intrigued by this line in the Novartis/Vernalis article you cited -

Does Hsp70 limit the anticancer potential of Hsp90 inhibitors?
Hsp70 is induced in response to Hsp90 inhibition by small molecules in almost all of the cell lines tested...


Does that imply they didn't test/have any results for the Neutec 'grab' (antibody) ?
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