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Biotech / Medical : Amgen Inc. (AMGN)
AMGN 297.00+0.2%Nov 4 3:59 PM EST

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To: nigel bates who wrote (1304)10/11/2006 8:51:19 PM
From: tuck   of 1906
 
>>Anyone know what happened to AMG-108 (anti IL1) ?<<

You remember this whiffed in osteoarthritis, right? The RA trial is still ongoing. Note info was updated by Amgen in October of 2006:

clinicaltrials.gov

Still, this commenced about two years ago. With the endpoint miss in OA, it's probably a good thing that apparently no p value is being sacrificed for an interim look, hence no news. I suspect enrollment has been slow, since there are several agents out there that work reasonably well, as you know. I wouldn't put it in your valuation model, or, if you are looking at it from the perspective of a competitor, I wouldn't view it as a serious or impending threat. Investor relations might give more detail -- such as when further information is expected -- if you care enough to call?

Cheers, Tuck
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