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Biotech / Medical : Exelixis, Inc. (EXEL)
EXEL 40.33+6.4%Nov 5 3:59 PM EST

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To: dr.praveen who wrote (307)11/8/2006 8:46:47 AM
From: dr.praveen   of 930
 
Reference: Exelixis drugs,targets & Indications

Drug,Target,Status,Indication

XL119* Topoisomerase 2 Phase III Biliary Tract Cancer

XL999** VEGFR2, PDGFR,FGFR, FLT3 Phase II Renal Cell Carcinoma, Colon, Ovarian,NSCLC, AML, Multiple Myeloma

XL647** VEGFR2, EGFR,HER2 Phase II NSCLC

XL784** ADAM10, MMP-2 Phase II Diabetic Nephropathy

XL880 c-MET, VEGFR2 Phase II Papillary Cell Carcinoma

XL820 c-KIT, VEGFR2,PDGFR Phase I Solid Tumors

XL844 CHK1, CHK2 Phase I Solid Tumors, Hematologic Malignancies

XL184 c-MET, VEGFR2 Phase I Solid Tumors

XL228 ABL, IGF1R, SRC IND Filed Solid Tumors, Hematologic Malignancies

XL281 RAF IND Filed Solid Tumors

XL418 AKT, S6K Preclinical Solid Tumors

XL518 MEK Preclinical Solid Tumors

XL765 PI-3K, mTOR Preclinical Solid Tumors

XL147 PI-3K Preclinical Solid Tumors

XL019 JAK2 Preclinical Myeloid/Lymphoid Malignancies

XL550*** Mineralocorticoid Receptor Preclinical Hypertension

XL335*** Farsenoid Receptor Preclinical Atherosclerosis

EXEL2255*** Liver X Receptor Preclinical Atherosclerosis
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