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Biotech / Medical : MEDX ... anybody following?
MEDX 31.84+0.8%Nov 10 3:26 PM EST
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To: nigel bates who wrote (1530)11/24/2006 11:21:53 AM
From: scaram(o)uche  Read Replies (1) of 2240
 
One of those "who??" licenses where you never expect to hear anything in the future. Cool.

J Neuroimmunol. 2006 Aug;177(1-2):132-5. Epub 2006 Jun 30.

Elevated serum soluble vascular adhesion protein-1 (VAP-1) in patients with active relapsing remitting multiple sclerosis.

Airas L, Mikkola J, Vainio JM, Elovaara I, Smith DJ.
Department of Neurology and MediCity Research Laboratory, University of Turku, PO Box 52, 20521Turku, Finland. laura.airas@utu.fi

Vascular adhesion protein-1 (VAP-1) is an endothelial cell molecule which controls leukocyte infiltration into tissues. Elevated serum soluble VAP-1-levels have been described in certain diseases with an inflammatory component. VAP-1 expression or function has not previously been studied in multiple sclerosis (MS). We report here that the concentration of soluble VAP-1 in serum is significantly higher in multiple sclerosis patients with ongoing inflammatory activity, as demonstrated by gadolinium-enhancing MRI lesions, when compared to patients with no gadolinium-enhancing lesions (555+/-195 vs. 388+/-102 ng/ml, p=0.0068). We propose that VAP-1 might participate in controlling leukocyte entry into inflamed brain.
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