Ligand (LGND) Breakout! Message Board

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Biotech / Medical : Ligand (LGND) Breakout!

LGND 206.72

+0.1%

3:59 PM EST

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To: Andrew H who wrote (8007)	9/29/1997 2:37:00 PM
From: Abuckatatime	of 32384

Hope the elevation of serum triglycerides apparently seen in some patients taking the higher doses of Targretin hasn't scared off buyers. I seriously doubt it. We will have to wait on release of more data to see how much of a hypertriglyceridemic effect Targretin may have. Hypertriclyceridemia can be an additional risk factor for heart disease and is not uncommon in type 2 diabetes. Fortunately, TZD's, with their hypotriglyceridemic properties, will likely be prescribed along with Targretin and other RXR agonists in the treatment of DM so that any potential risk of raising serum triglyceride levels will be minimized.

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