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Biotech / Medical : Agouron Pharmaceuticals (AGPH)
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To: Joe E. who wrote (1923)9/30/1997 2:20:00 AM
From: Henry Niman   of 6136
 
Joe, I didn't quote anything, I just uploaded the AP article. I had seen the AGPH article in thestreet and was curious as to what shareholder's thought. I came over here and several were asking why AGPH was down or why they had been downgraded. I suggested that the read the article.

I think that the patients were switched a bit on the late side, but the data did suggested that in certain instances, switching does no good. I think that the NY Times ran an article on PI failures a month or two ago and they came to similar conclusions (patients that begin PIs with a high viral load and a long treatment history don't do well - they didn't name any names as far as PIs are concerned).

I haven't followed the conference that closely, but when posters start attacking the media for reporting news at the conference, I get a bit concerned. When PI's first became popular, I predicted that resistant strains would develop. Its a simple numbers game. Undetectable doesn't mean eliminated, and eventually resistance strains will occur if the initial number is high enough, and widespread (in the field) results may not be the same as well controlled studies using highly motivated patients.

I suggest that you focus on the science and not the media or posters.
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