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Biotech / Medical : Stem Cell Research
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From: nigel bates1/24/2007 6:41:43 AM
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ReNeuron secures funding from Michael J. Fox Foundation for ReN004 stem cell therapy for Parkinson's disease

Guildford, UK, 24 January 2007: ReNeuron Group plc (LSE: RENE) today announces that it has been awarded a grant from the US-based Michael J. Fox Foundation for Parkinson's Research (MJFF) to develop its ReN004 stem cell therapy for
Parkinson's disease. The award was made under MJFF's Therapeutics Development Initiative, designed to catalyse and expand industry investment in pre-clinical Parkinson's drug development.

ReNeuron has previously presented data showing that its ReN004 candidate stem cell lines have the potential to reverse the neurological deficits in pre-clinical models of Parkinson's disease. The data indicated good in vivo survival of the cell lines and expression of the appropriate markers for dopaminergic neurons, the cell type deficient in Parkinson's patients. The MJFF grant will allow ReNeuron to build on this pre-clinical data and also develop a biodegradable delivery matrix which the Company believes will be required to successfully implant the required cell type into Parkinson's patients. The grant will fund the ReN004 programme over the next year, accelerating its progress towards the clinic.

In addition to its Parkinson's disease programme, ReNeuron has recently filed for approval to commence initial clinical studies in the US with its lead ReN001 stem cell therapy for stroke. The Company is also developing stem cell therapies for Huntington's disease, Type 1 diabetes and diseases of the retina...
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