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Biotech / Medical : Indications -- Psoriasis/Chronic Inflammation
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From: Ian@SI2/2/2007 2:35:11 PM
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1:06PM Genentech announces "positive results" from a Phase IV study of Raptiva in patients with moderate-to-severe hand and foot psoriasis (DNA) 87.59 +0.37 : Co announced results from a Phase IV study of Raptiva that showed statistically significant improvement in patients with chronic moderate-to-severe plaque psoriasis involving the hands and feet. The 12-week study is the first randomized, double blind, placebo-controlled trial to evaluate a biologic agent in the treatment of this uniquely challenged subpopulation of psoriasis patients. The results were presented as a poster at the 65th annual meeting of the American Academy of Dermatology in Washington, D.C. Adverse events in this study were consistent with previous company- sponsored clinical trials with Raptiva.

1:05PM Abbott Labs: Psoriasis patients show significant improvement in symptoms with Abbott's HUMIRA in New Phase III Study (ABT) 52.69 0.18 : ABT notes that Psoriasis patients experienced a significant reduction in the signs of their disease when treated with Abbott's HUMIRA, and they were significantly less likely to have their disease signs worsen when they used HUMIRA continuously, new study results show. The safety profile of HUMIRA was found to be consistent with earlier clinical studies of HUMIRA in psoriasis and rheumatoid arthritis. These findings from the REVEAL study of patients with moderate to severe psoriasis were presented today at the American Academy of Dermatology annual meeting in Washington, D.C. REVEAL is the second Phase III study to show positive results for HUMIRA in psoriasis. Abbott will submit REVEAL results as part of a regulatory application for a psoriasis indication in the United States and Europe, expected during the first half of 2007.
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