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Biotech / Medical : Synta Pharmaceuticals
SNTA 0.343+26.6%Jul 22 5:00 PM EST

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From: keokalani'nui2/8/2007 12:45:40 PM
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SNTA

Price: $9.50
MC: $332m
c/s: 35m
Cash : $100m
Burn: $70m
IPO: $10.00 on 2/6/07 (Bear Stearns, Lehman, Lazard and Montgomery)
Retained Deficit ($224m, during development stage!)

(my) Summary of value/issues

1. STA-4783, Metastatic Melanoma, an HSP70 agonist, expect P3 to start mid-07. Questions about whether indications will be expanded, but it was underdosed nsclc vs MM. $175m.

2. Aplimod for RA and CVID in P2. Failed for Crohn’ s and psoriasis. $0.

3. STA-9090, HSP90. IND promised 1H07. $30m.

4. STA-9584, anti-angiogenesis, preclinical. $0.

5. CRAC ion channel inhibition on immune cells, Lead Optimization. This is an interesting program one to watch and if it produces an IND it might get significant attention. For now, $0.

6. Will need to go back to the market with another 5m shares soon. Huge lock-up unloads in 6 months.
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