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Biotech / Medical : Alexion Pharmaceuticals, Inc. (ALXN)
ALXN 182.500.0%Jul 28 5:00 PM EST

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To: keokalani'nui who wrote (768)3/27/2007 10:59:48 AM
From: rkrw  Read Replies (1) of 824
 
Wilder, good question on why not $1M, where do you draw a line?

<<We considered many factors when establishing a price for Soliris. These included the rarity of this disabling and life threatening disease, the compelling clinical benefits that PNH patients experience with Soliris therapy, which is clearly represented in the approved label, the cost of discovery, development, and production, and of ongoing research of therapeutic complement inhibition. And the cost to sustain Alexion's commitment to the PNH community. Based on these factors, the annual wholesale cost of Soliris therapy is $389,000. This cost is comparable to the cost of other medicines for disabling and life threatening ultra
orphan diseases, which are often dosed by weight. This annual cost has not been adjusted for typical chronic drug compliance
or for other commitment to serve uninsured patients. The outlined commercial strategies will enable us to deliver on our patient care and patient assistance commitments to patients with this rare disabling and life threatening disease and to achieve our goal that every patient who can benefit from Soliris will have access to Soliris.>>>

The thing is at any less than $389K they wouldn't be able to sustain their commitment to the pnh community. How much does sustaining a commitment cost?
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