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Biotech / Medical : Stem Cell Research
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From: nigel bates4/17/2007 4:52:27 AM
   of 495
 
ReNeuron receives notice of European patent grant covering key neural stem cell
lines

Guildford, UK, 17 April 2007: ReNeuron Group plc (LSE: RENE.L) today announced
that it has received a notification of grant from the European Patent Office
concerning a patent application covering the composition, manufacture and use of
three key human neural stem cell lines.

The patent (No. 05255932.5) contains claims covering the production of the cell
lines and their use as a treatment for stroke, Huntington's disease, Alzheimer's
disease, traumatic brain injury and Creutzfeld-Jacob disease (CJD). The patent
claims also encompass the use of these cell lines in non-therapeutic
applications such as cell-based screens for testing neurological drug
candidates. Of the three cell lines concerned, one has been taken forward as
ReNeuron's ReN001 treatment for stroke and one is being developed as the
Company's ReN005 treatment for Huntington's disease. The third is a back-up cell
line derived from the hippocampus region of the brain.

Equivalent patent applications to the above European patent have been filed by
the Company in the US and other significant territories. Overall, ReNeuron has
written or exclusively licensed over 55 issued patents and over 70 further
patent applications. Of these, over 30 patents have issued in the key European
and US territories.
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