CV Therapeutics Inc: No Real Change to the Thesis MORGAN STANLE 2007-04-24 19:07 (New York)
NORTH AMERICA April 24, 2007 (CVTX.O) CV Therapeutics Inc CV Therapeutics Inc: No Real Change to the Thesis Steven Harr, M.D. +1 (1)212 761 3805 Morgan Stanley & Co. Incorporated Conclusion: Higher than expected 1Q Ranexa sales and decreased operating expenses were a step in the right direction, and the operating expense cuts are consistent with our expectations that cuts to the infrastructure are inevitable given current business trends and the cash burn (our model was aggressive in 2008 and beyond). The full impact of the MERLIN data will likely take over a year to emerge (the JAMA editorial highlights our view that Ranexa is a good drug for patients with symptoms after trying 1-2 other therapies), and we still believe that safety with a lack of outcomes effect should be enough to win a broader label and use, but not enough to drive meaningful profits. What's New: Ranexa sales of $12M were greater than our $9M estimate, and lower operating expenses drove loss per share of ($0.93) versus both our ($1.14) and the ($1.03) consensus estimate. Separately, MERLIN data were published in JAMA. Expense guidance of $275-$285M is under review, and given our view that expense cuts are inevitable, we are accelerating some of these into 2007, which combined with a modest increase in 2007E Ranexa sales, lowers our 2007E loss (but no changes in out years). Implications: Although the initial reaction to today's financial results will likely be a modest positive, we continue to see significant risk to this company given its: 1) high burn rate, 2) leveraged balance sheet, and 3) need to raise significant capital going forward. A Ranexa partnership may provide the company with a financial reprieve (and lead to broader strategic discussions), but this business remains under tremendous pressure and we see little reason to own the stock at these levels. Stock Rating: Underweight-V Industry View: In-Line ModelWare EPS actual: (Dec 2005) USD (5.66); (Dec 2006) USD (5.49) ModelWare EPS estimate: (Dec 2007) USD (3.02); (Dec 2008) USD (1.73) Consensus EPS actual: (Dec 2005) USD (5.66); (Dec 2006) USD (5.57) Consensus EPS estimate: (Dec 2007) USD (3.32); (Dec 2008) USD (1.74) Share Price: USD 7.89 (Apr 24, 2007) Target Price: NA Market Cap: (mm) USD 453 __________ |