Illumina Reports Financial Results for Second Quarter 2007 Tuesday July 24, 4:01 pm ET  
  Revenue Increases 103% Over Prior Year; $24.5 Million in Cash Flow                             from Operations 
  SAN DIEGO--(BUSINESS WIRE)--Illumina, Inc. (NASDAQ:ILMN - News) today announced its financial results for the second quarter of 2007.
  For the second quarter of 2007, Illumina reported revenue of $84.5 million, a 103% increase over the $41.6 million reported in the second quarter of 2006. This represents the Company's 24th consecutive quarter of revenue growth. The Company reported second quarter net income of $9.3 million, or $0.16 per diluted share, compared to net income of $6.8 million, or $0.14 per diluted share in the comparable period of 2006. Net income for the second quarter includes non-cash charges of $0.8 million associated with the January 26, 2007 acquisition of Solexa, and $7.8 million in non-cash stock compensation expense associated with SFAS No. 123R. Excluding the impact of these items and net of pro forma tax expense, Illumina's net income on a non-GAAP basis was $16.8 million, or $0.29 per diluted share, for the second quarter of 2007, compared to $10.1 million, or $0.21 per diluted share for the second quarter of 2006.
  The combined gross margin for products and services in the second quarter of 2007 was 64.3%, compared to 67.0% in the comparable period of 2006. Excluding the effect of the non-cash charges associated with the acquisition of Solexa and stock compensation mentioned above, the combined gross margin of products and services was 65.7% for the second quarter of 2007 compared to 67.9% in the prior year period. The year-over-year decrease in gross margin was primarily attributable to a change in product mix.
  Research and development (R&D) expenses for the second quarter of 2007 were $18.2 million, compared to $8.6 million in the second quarter of 2006. R&D expenses include $2.5 million and $0.9 million in non-cash stock compensation expense in the second quarter of 2007 and 2006, respectively. Excluding these non-cash charges, R&D expenses as a percentage of revenues were 18.6%, compared to 18.5% in the prior year period.
  Selling, general and administrative (SG&A) expenses for the quarter were $23.3 million, compared to $12.9 million for the second quarter of 2006. SG&A expenses include $4.3 million and $2.1 million of non-cash stock compensation expense in the second quarter of 2007 and 2006, respectively. Excluding these non-cash charges, SG&A expenses as a percentage of revenues were 22.5%, compared to 26.0% in the prior year period.
  The Company generated $24.5 million in cash from operations during the second quarter of 2007, compared to $14.9 million in the comparable quarter of 2006. Depreciation and amortization was $3.6 million and capital expenditures were $6.7 million during the quarter. The Company ended the quarter with $343.3 million in cash and short-term investments, compared to $326.8 million as of April 1, 2007. This increase in cash was primarily attributable to cash from operations.
  Highlights since our last earnings release: Announced the commercialization of sequencing-based small RNA         and gene expression profiling applications to be run on the         Illumina Genome Analyzer. Announced a multi-million dollar collaboration with the         University of Pennsylvania, The Broad Institute and the CARe         Consortium to provide custom iSelect arrays to test more than         120,000 samples for over 55,000 single-nucleotide         polymorphisms (SNPs) associated with cardiovascular disease. Announced the shipment of the Human1M DNA Analysis BeadChip, a         single-chip solution containing more than one million (SNPs),         in addition to novel CNV content developed in collaboration         with deCODE genetics not currently available on any other         array or public database. Announced that, as of June 13th, 2007, the Company had         received more than 75 orders for our Genome Analyzer platform         with significant demand across genome centers, core         laboratories, industrial laboratories and individual academic         centers worldwide. Subsequent to the second quarter, the         Company received an order for 20 Genome Analyzers from a         single customer. Announced that Germany's National Genome Research Network         (NGFN) selected the Company's Infinium® HumanCNV370-Duo,         HumanHap300-Duo, and HumanHap550 BeadChips to genotype 8,000         patients and controls to investigate genetic variations to         better understand underlying causes of 25 complex diseases. 
  Financial Outlook and Guidance
  The non-GAAP financial guidance discussed below excludes the effect of non-cash stock compensation expense and non-cash charges related to the acquisition of Solexa, Inc. (see table which reconciles these non-GAAP financial measures to the related GAAP measures).
  Guidance for Fiscal 2007 We expect fiscal 2007 revenue to be between $335 and $345         million. This represents an increase of $30 million above the         guidance we provided on April 24, 2007. Research and development expenses are expected to be between         $60 and $70 million, $3 million above our previous guidance. Selling, general and administrative expenses are expected to         be between $75 and $85 million, $3 million above our previous         guidance. We expect the effective tax rate for the calculation of         non-GAAP financial measures to be approximately 32%. We expect non-GAAP net income to be between $60 and $66         million, or $1.00 to $1.10 per diluted share, assuming fully         diluted weighted-average shares of 60 million. This represents         an increase of $5 million above the low end of the guidance we         provided on April 24, 2007. We expect non-cash stock compensation expense related to SFAS         No. 123R to be approximately $31 million, or $0.52 per diluted         share. 
  Guidance for Q3 2007 The Company expects third quarter total revenue to be between         $88 and $92 million. Management expects non-GAAP net income to         be between $16 and $18 million, or $0.26 and $0.30 per diluted         share, assuming quarterly fully diluted weighted-average         shares of 60 million.
  Quarterly Conference Call Information
  Our conference call will begin at 2:00 pm Pacific Time (5:00 pm Eastern Time) on July 24, 2007. Interested parties may listen to the call by dialing 866.356.4279 (passcode: 11296577), or if outside North America, by dialing +1.617.597.5394 (passcode: 11296577). Individuals may access the live webcast under the "Corporate/Investor Information" tab of Illumina's web site at www.illumina.com.
  About Illumina
  Illumina is a leading developer, manufacturer and marketer of next-generation life science tools and integrated systems for the large scale analysis of genetic variation and biological function. Using our proprietary technologies, we provide a comprehensive line of products and services that currently serve the sequencing, genotyping, and gene expression markets, and we expect to enter the market for molecular diagnostics. Our customers include leading genomic research centers, pharmaceutical companies, academic institutions, clinical research organizations and biotechnology companies. Our tools provide researchers around the world with the performance, throughput, cost effectiveness and flexibility necessary to perform the billions of genetic tests needed to extract valuable medical information from advances in genomics and proteomics. We believe this information will enable researchers to correlate genetic variation and biological function, which will enhance drug discovery and clinical research, allow diseases to be detected earlier and permit better choices of drugs for individual patients.
  Statement Regarding Use of Non-GAAP Financial Measures
  The Company has reported non-GAAP results for diluted net income per share, net income, gross margins and free cash flow in addition to, and not as a substitute for, or superior to, financial measures calculated in accordance with GAAP.
  The Company's financial results under GAAP include substantial non-cash charges related to stock compensation expense and its acquisition of Solexa, Inc. in January 2007. Management believes that presentation of operating results that exclude these non-cash charges provides useful supplemental information to investors that facilitates analysis of the Company's core operating results and comparison of operating results across reporting periods. Management believes that this supplemental non-GAAP information is therefore useful to investors in analyzing and assessing the Company's past and future operating performance.
  The Company encourages investors to carefully consider its results under GAAP, as well as its supplemental non-GAAP information and the reconciliation between these presentations, to more fully understand its business. Reconciliations between GAAP and non-GAAP results are presented in the tables of this release.
  "Safe Harbor" Statement under the Private Securities Litigation Reform Act of 1995: this release may contain forward-looking statements that involve risks and uncertainties. Among the important factors that could cause actual results to differ materially from those in any forward-looking statements are the costs and outcome of Illumina's litigation with Affymetrix and our ability (i) to integrate effectively our recent acquisition of Solexa, Inc., (ii) to develop and commercialize further our BeadArray(TM), VeraCode(TM) and Solexa® technologies and to deploy new gene expression and genotyping products and applications for our technology platforms, (iii) to manufacture robust micro arrays and Oligator® oligonucleotides, (iv) to integrate and scale our VeraCode technology, (v) to scale further oligo synthesis output and technology to satisfy market demand derived from our collaboration with Invitrogen, together with other factors detailed in our filings with the Securities and Exchange Commission including our recent filings on Forms 10-K and 10-Q or in information disclosed in public conference calls, the date and time of which are released beforehand. We disclaim any intent or obligation to update these forward-looking statements beyond the date of this release.                             Illumina, Inc.                  Condensed Consolidated Balance Sheets                             (In thousands)
                                        July 1, 2007   December 31, 2006                                                             (1)                                      --------------  -----------------                                       (unaudited) ASSETS
  Current assets:  Cash and cash equivalents           $       81,117  $          38,386  Short-term investments                     262,145             92,418  Accounts receivable, net                    57,441             39,984  Inventory, net                              42,898             20,169  Prepaid expenses and other current   assets                                      8,585              2,769                                      --------------  -----------------
     Total current assets                     452,186            193,726
  Property and equipment, net                  36,683             25,634 Investment in Solexa                              -             67,784 Goodwill                                    248,778              2,125 Acquired intangible assets, net              23,296                  - Other assets, net                            12,631             11,315                                      --------------  -----------------
     Total assets                      $      773,574  $         300,584                                      ==============  =================
  LIABILITIES AND STOCKHOLDERS' EQUITY
  Current liabilities:  Accounts payable                    $       22,495  $           9,853  Accrued liabilities and current   portion of long-term debt                  54,112             23,923                                      --------------  -----------------
     Total current liabilities                 76,607             33,776
  Long-term debt                              400,000                  - Other long-term liabilities                  10,132             19,466 Stockholders' equity                        286,835            247,342                                      --------------  -----------------
     Total liabilities and     stockholders' equity             $      773,574  $         300,584                                      ==============  =================
  (1) The condensed consolidated balance sheet as of December 31, 2006  has been derived from the audited financial statements as of that  date.
                              Illumina, Inc.            Condensed Consolidated Statements of Operations                (In thousands, except per share amounts)                              (Unaudited)
                                       Three Months                                          Ended       Six Months Ended                                     --------------- ------------------                                     July 1, July 2,  July 1,   July 2,                                       2007    2006     2007      2006                                     ------- ------- ---------- -------
  Revenue:  Product                            $74,297 $36,403 $ 135,562  $59,664  Service and other                   10,086   4,795    20,847   10,062  Research                               152     379       276      953                                     ------- ------- ---------- -------
   Total revenue                       84,535  41,577   156,685   70,679                                     ------- ------- ---------- -------
  Costs and expenses:  Cost of revenue (including non-   cash stock compensation expense   of $1,033, $350, $1,979 and $600,   respectively)                      30,141  13,576    55,262   22,869  Research and development   (including non-cash stock   compensation expense of $2,497,   $878, $4,428 and $1,836,   respectively)                      18,184   8,587    34,140   16,803  Selling, general and   administrative (including non-   cash stock compensation expense   of $4,255, $2,099, $9,056 and   $4,022, respectively)              23,297  12,891    46,930   25,025  Amortization of acquired   intangible assets                     662       -     1,104        -  Acquired in-process research and   development                             -       -   303,400        -                                     ------- ------- ---------- -------
   Total costs and expenses            72,284  35,054   440,836   64,697                                     ------- ------- ---------- -------
  Income (loss) from operations        12,251   6,523  (284,151)   5,982
  Interest and other income, net        2,343     856     5,066    1,424                                     ------- ------- ---------- -------
  Income (loss) before income taxes    14,594   7,379  (279,085)   7,406
  Provision for income taxes            5,330     611     9,727      742                                     ------- ------- ---------- -------
  Net income (loss)                   $ 9,264 $ 6,768 $(288,812) $ 6,664                                     ======= ======= ========== =======
  Net income (loss) per basic share   $  0.17 $  0.16 $   (5.39) $  0.16                                     ======= ======= ========== ======= Net income (loss) per diluted share    0.16    0.14     (5.39)    0.14                                     ======= ======= ========== =======
  Shares used in calculating basic  net income (loss) per share         53,778  43,528    53,604   42,502                                     ======= ======= ========== ======= Shares used in calculating diluted  net income (loss) per share         58,061  47,330    53,604   46,252                                     ======= ======= ========== =======
                              Illumina, Inc.             Condensed Consolidated Statements of Cash Flow                             (In thousands)                              (Unaudited)
                                Three Months Ended    Six Months Ended                               ------------------- --------------------                               July 1,   July 2,    July 1,   July 2,                                  2007      2006      2007       2006                               --------- --------- ---------- ---------
  Net cash provided by  operating activities         $ 24,483  $ 14,903  $  39,126  $ 17,263
  Net cash used in investing  activities                    (69,514)   (9,501)  (103,924)  (16,729)
  Net cash provided by  financing activities            2,465    97,928    107,415   101,030
  Effect of foreign currency  translation on cash and cash  equivalents                       154      (124)       114      (136)                               --------- --------- ---------- ---------
  Increase (decrease) in cash  and cash equivalents          (42,412)  103,206     42,731   101,428
  Cash and cash equivalents,  beginning of period           123,529    49,044     38,386    50,822                               --------- --------- ---------- ---------
  Cash and cash equivalents,  end of period                $ 81,117  $152,250  $  81,117  $152,250                               ========= ========= ========== =========
  Calculation of Free Cash Flow  (a):
  Net cash provided by  operating activities         $ 24,483  $ 14,903  $  39,126  $ 17,263
  Purchases of property and  equipment                      (6,686)   (4,957)    (9,925)   (9,149) Cash paid for intangible  assets                              -       (15)         -       (15)                               --------- --------- ---------- ---------
  Free cash flow                $ 17,797  $  9,931  $  29,201  $  8,099                               ========= ========= ========== =========
  (a) Free cash flow, which is a non-GAAP financial measure, is  calculated as net cash provided by operating activities reduced by  purchases of property and equipment and cash paid for intangible  assets.  Free cash flow is useful to management as it is one of the  metrics used to evaluate our performance and to compare the Company  with other companies in our industry.  However, our calculation of  free cash flow may not be comparable to similar measures used by  other companies.
                              Illumina, Inc.                    Results of Operations - Non-GAAP                (In thousands, except per share amounts)                              (Unaudited)
  AN ITEMIZED RECONCILIATION BETWEEN GAAP AND NON-GAAP NET INCOME (LOSS)  PER SHARE IS AS FOLLOWS:
                                      Three Months     Six Months Ended                                          Ended                                    ---------------- ------------------                                    July 1,  July 2,  July 1,   July 2,                                      2007     2006     2007      2006                                    -------- ------- ---------- -------
  GAAP net income (loss) per share -  diluted                           $  0.16  $  0.14 $   (5.39) $  0.14
  Pro forma impact on weighted  average shares                          -        -      0.41        -
  Adjustment to net income (loss),  as detailed below                    0.13     0.07      5.49     0.14                                    -------- ------- ---------- -------
  Non-GAAP net income per share -  diluted (a)                       $  0.29  $  0.21 $    0.51  $  0.28                                    ======== ======= ========== =======
  Shares used in calculating non-  GAAP diluted net income per share  58,061   47,330    58,040   46,252                                    ======== ======= ========== =======
  AN ITEMIZED RECONCILIATION BETWEEN GAAP AND NON-GAAP NET INCOME (LOSS)  IS AS FOLLOWS:
  GAAP net income (loss)             $ 9,264  $ 6,768 $(288,812) $ 6,664
  Non-cash stock compensation  expense                             7,785    3,327    15,463    6,458
  Amortization of acquired  intangible assets                     662        -     1,104        -
  Amortization of inventory  revaluation costs                     126        -       942        -
  Acquired in-process research and  development expense                     -        -   303,400        -
  Pro forma tax expense (b)             (990)       -    (2,529)       -                                    -------- ------- ---------- -------
  Non-GAAP net income (a)            $16,847  $10,095 $  29,568  $13,122                                    ======== ======= ========== =======
  (a)  Non-GAAP diluted net income per share and net income excludes the  effect of non-cash stock compensation expense, as well as the  amortization of acquired intangible assets, amortization of inventory  revaluation costs on products sold that were previously written-up  under purchase accounting rules and acquired in-process research and  development expense related to the Company's acquisition of Solexa,  Inc. in January 2007.  Management regards non-GAAP net income and  non-GAAP diluted net income per share as key indicators of the  Company's core operating performance and are major factors in  determining management's bonus compensation each year.  Management  has excluded the effects of these items in these measures to assist  investors in analyzing and assessing our past and future core  operating performance.
  (b) Pro forma tax expense is higher than GAAP tax expense primarily  because certain acquisition related costs such as amortization of  acquired intangible assets and inventory revaluation costs, acquired  in-process research and development expense are deducted for GAAP  purposes but excluded for pro forma purposes.  In addition, GAAP net  income (loss) for the three and six months ended July 1, 2007  includes non-cash stock compensation expense, which is deducted for  GAAP purposes but excluded for pro forma purposes. This deduction  produces a GAAP-only tax benefit, which is added back for pro forma  presentation.
                              Illumina, Inc.              Results of Operations - Non-GAAP (continued)                              (Unaudited)
  AN ITEMIZED RECONCILIATION BETWEEN GAAP AND NON-GAAP GROSS MARGIN IS  AS FOLLOWS:
  GAAP product and services gross margin         64.3% 67.0% 64.7% 67.2%
  Non-cash stock compensation expense             1.2%  0.9%  1.2%  0.9%
  Amortization of inventory revaluation costs     0.2%  -     0.6%  -                                                ----- ----- ----- -----
  Non-GAAP product and services gross margin (a) 65.7% 67.9% 66.5% 68.1%                                                ===== ===== ===== =====
  (a)  Non-GAAP product and services gross margin excludes the effect of  non-cash stock compensation expense and the amortization of inventory  revaluation costs.  Management regards non-GAAP product and services  gross margin as a key measure of the effectiveness and efficiency of  the Company's manufacturing processes, product mix and the average  selling prices of the Company's products and services.
                              Illumina, Inc.     Reconciliation of GAAP to Non-GAAP Financial Guidance Summary                (In thousands, except per share amounts)
  The financial guidance provided below is an estimate based on  information available as of July 24, 2007. The Company's future  performance and financial results are subject to risks and  uncertainties, and actual results could differ materially from the  guidance set forth below. Some of the factors that could affect the  Company's financial results are stated above in this press release.  More information on potential factors that could affect the Company's  financial results is included from time to time in the Company's  public reports filed with the SEC, including the Company's Form 10-K  for the fiscal year ended December 31, 2006, the Company's Form 10-Q  for the quarter ended April 1, 2007 and the Company's Form 10-Q for  the quarter ended July 1, 2007 to be filed with the SEC. The Company  assumes no obligation to update any forward-looking statements or  information, which speak as of their respective dates.
                                 Fiscal Year 2007 Financial Guidance                                               Summary                             ------------------------------------------                                             Non-GAAP                                  GAAP      Adjustments      Non-GAAP                             -------------- -----------    ------------ Revenue                      $335 - 345                   $335 - 345                                 million                      million                             ==============                ============ Research and development    $68.9 - 78.9     ($8.9    (a)  $60 - 70  expenses                       million      million)        million                             ============== ===========    ============ Selling, general and        $93.1 - 103.1    ($18.1   (a)  $75 - 85  administrative expenses        million      million)        million                             ============== ===========    ============ Net income (loss)             ($277.8 -      $337.8   (b)  $60 - 66                                 271.8        million         million                                million)                             ============== ===========    ============ Diluted net income (loss)                             (b)  per share                  ($4.63 - 4.53)    $5.63       $1.00 - 1.10                             ============== ===========    ============
                                  Q3 2007 Financial Guidance Summary                             ------------------------------------------                                             Non-GAAP                                  GAAP      Adjustments      Non-GAAP                             -------------- -----------    ------------
  Revenue                       $88 - 92                     $88 - 92                                 million                      million                             ==============                ============ Net income                   $7.1 - 9.1       $8.9    (b)  $16 - 18                                 million      million         million                             ============== ===========    ============ Diluted net income per share $0.11 - 0.15     $0.15   (b) $0.26 - 0.30                             ============== ===========    ============
  (a) These adjustments reflect the estimated impact of non-cash stock  compensation expense for fiscal year 2007.
  (b) These adjustments reflect the estimated impact on net income  (loss) and diluted net income (loss) per share for fiscal year 2007  and Q3 2007 from the non-GAAP adjustments related to non-cash stock  compensation expense, as well as the amortization of acquired  intangible assets, amortization of inventory revaluation costs on  products sold that were previously written-up under purchase  accounting rules and acquired in-process research and development  expense related to the Company's acquisition of Solexa, Inc. in  January 2007.
   Contact: Illumina, Inc. Christian O. Henry, Chief Financial Officer 1.858.202.4508 chenry@illumina.com Peter J. Fromen, Sr. Director, Investor Relations 1.858.202.4507 pfromen@illumina.com
  Source: Illumina, Inc. |