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Biotech / Medical : Ligand (LGND) Breakout!
LGND 197.62+0.1%Dec 24 12:59 PM EST

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To: Andrew H who wrote (8538)10/7/1997 7:27:00 AM
From: DrJerry   of 32384
 
Andy- the use of bromocriptine at present is limited
because of side effects- the most common setting is
pituitary tumors associated with abnormal prolactin
levels- its use in Parkinsonism is not very common-
for intended use with diabetes I would have major
reservations namely because as an ergot derivative there
would be strong warnings for patients with coronary
disease (because of propensity to provoke coronary spasm)
and hypertension (because of both hypo and hypertensive
episodes associated with the drug). Since diabetics in
large part have both disease entities I would see a
limited market.
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