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Biotech / Medical : Mining Cholesterol
EVR 331.69+1.0%Dec 5 4:00 PM EST

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From: E. Charters7/31/2007 2:34:45 AM
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Indirubin

This substance is made from the dye indigo.

It is found effective in culture medium on breast and other tumours.

It was widely used in China on luekemia.

Indirubin, a compound isolated from a traditional Chinese herbal medicine, is an effective treatment for chronic myelocytic leukemia. Studies have shown hat indirubin or its derivatives act by inhibiting excessive signaling of the cyclin-dependent kinases and Stat3 metabolic pathways. The indirubin compounds are effective in cell culture lines of mammary carcinoma, large cell lung carcinoma, and prostate cancer.

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