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Biotech / Medical : Gene therapy
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To: Mike McFarland who wrote (240)11/30/2007 11:16:04 AM
From: DNA-Jock   of 319
 
As I said so many years ago:
"While it would be nice if Kmiec & co-workers were able to show the generation of a piece of DNA that wasn't already floating around their lab (not done yet), I don't think their method will have any credibility until independently corroborated. In 2.5 years the silence has been impressive, and not for want of trying."
nature.com
fails to convince since:
1) no independent corroboration
2) the neomycin gene may be the most ubiquitous piece of DNA in the world - take a swab from any lab bench and you can PCR it up (trust me, the most difficult thing I ever had to do was use PCR to detect very low levels of neo DNA in tissue samples - the contamination problems were horrendous)
3) they've switched to S.cerevisiae, for crying out loud, an organism that loves homologous recombination so much that you can't get it to do non-homologous. ALmost the exact opposite of mammals.
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