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Biotech / Medical : Rigel Pharmaceuticals, Inc. (RIGL)
RIGL 37.87+33.8%Nov 5 3:59 PM EST

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From: mopgcw12/5/2007 11:40:56 AM
   of 566
 
Rigel Announces Presentations at the 2007 American Society of Hematology (ASH) Meeting
Wednesday December 5, 7:30 am ET

SOUTH SAN FRANCISCO, Calif., Dec. 5 /PRNewswire-FirstCall/ -- Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL - News) today announced a number of presentations being given on Rigel product candidates at the upcoming American Society of Hematology Meeting and Exposition, at the Georgia World Congress Center in Atlanta, Georgia, December 8-11, 2007.

Rigel Poster Presentations

R935788: A phase 2, single center, open label, efficacy and safety,
ascending dose, pilot study for the treatment of adult Immune
Thrombocytopenic Purpura (ITP)
Saturday, December 8, 2007 5:30 p.m. - 7:30 p.m.
Session Name -- ITP, TTP and HIT
Poster #464

Targeting myeloproliferative diseases with JAK2 inhibitors
Monday, December 10, 2007 5:00 p.m. - 7:00 p.m.
Session Name -- Myeloproliferative Syndromes: Therapy
Poster #769

Merck Serono Poster Presentation on Rigel's R763/AS703569

The novel aurora kinase inhibitor AS703569 shows potent anti-tumor
activity in Acute Myeloid Leukemia (AML)
Saturday, December 8, 2007 5:30 p.m. - 7:30 p.m.
Session Name - Acute Myeloid Leukemias: Therapy, excluding Transplantation
Poster #69

Other collaboration presentations with Rigel product candidates

Syk kinase inhibition by R406 inhibits BCR mediated B cell proliferation
and interferes with BCR signal transduction in primary tumor samples
Oral Presentation -- Tuesday, December 11, 2007 8:15 a.m.
Session Name -- Lymphoma: Pre-Clinical Chemotherapy and Biologic Agents --
Novel Agents, including Small Molecule Inhibitors

Mechanistic paradigm for combination signal transduction inhibitor therapy
in Zap70+ CLL involves bicompartmental functions of EZH2
Monday, December 10, 2007 5:00 p.m. - 7:00 p.m.
Session Name -- CLL: Clinical Biology
Poster #318

Constitutive activation of the protein tyrosine kinase syk in chronic
lymphocytic leukemia B cells
Saturday, December 8, 2007 5:30 p.m. - 7:30 p.m.
Session Name -- CLL: Molecular Biology
Poster #277

About Rigel (http://www.rigel.com)

Rigel is a clinical-stage drug development company that discovers and develops novel, small-molecule drugs for the treatment of inflammatory/autoimmune diseases and cancer, as well as viral and metabolic diseases. Our goal is to file one new investigational new drug (IND) application in a significant indication each year. Rigel has achieved this goal every year since 2002. Our pioneering research focuses on intracellular signaling pathways and related targets that are critical to disease mechanisms. Rigel's productivity has resulted in strategic collaborations with large pharmaceutical partners to develop and market our product candidates. Rigel has product development programs in inflammatory/autoimmune diseases such as rheumatoid arthritis, thrombocytopenia and asthma, as well as in cancer.
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