Statin mono-failure
HEART SCAN BLOG
Evan's first heart scan score in November, 2006 yielded a high score for a 56-year old male: 542.
So he put up little fuss when his doctor prescribed simvastatin at a high dose.
Evan's LDL cholesterol before simvastatin: 158 mg/dl
Evan's LDL cholesterol on simvastatin: 72 mg/dl.
By conventional standards, Evan has had an excellent response. The rest of his lipid (cholesterol panel) was unrevealing: HDL 62 mg/dl, triglycerides 78 mg/dl. Evan doesn't smoke, has a normal blood pressure, and he is not diabetic. That should do it, right?
So his doctor thought. So Evan asked if another heart scan was in order. In December, 2007, after one year of simvastatin, his second heart scan score: 705--a 30% increase over one year.
Recall that, with no effort at prevention whatsoever, the natural progression of heart scan scores is a 30% per year increase. Did simvastatin do nothing?
This is quite typical of people who do nothing more than take a statin drug. While some people do slow plaque growth (we say "decelerate") modestly on a statin drug, Evan's experience is not unusual: plaque continues to grow despite high-dose statin drug and an apparently favorable cholesterol panel.
In fact, I can count the number of people who reduced their heart scan scores taking a statin drug alone on one finger.
Statins do not represent a cure for heart disease. They cannot be used as sole therapy to reduce risk for heart attack. In fact, given sufficient time, the majority of people who do nothing more than follow this standard line of treatment (along with the equally lame low-fat diet, etc.) will have done nothing more than postpone their heart attack. Elimination of risk? Nope.
This is among the reasons we developed the Track Your Plaque approach. While not foolproof, I know of no better approach to seize control over plaque growth.
Additional conversations on clinical studies which, as with Evan's experience, demonstrated how statin drugs fail to slow plaque growth can be found in previous Heart Scan Blog posts:
Don't be satisfied with "deceleration"
Study review: Yet another Lipitor study
Copyright 2008 William Davis, MD
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