Endocannabinoid problems, severe, the invisible two neurons of the market.
The endocannabinoid system (ECS) tightly regulates the probability of neurotransmitter release in a host of neuronal tissues like the hippocampus, amygdala, basal ganglia, and cerebellum[1][2][3]. Data from immunologists, developmental biologists, and embryologists show that the ECS is also intimately involved in crosstalk between lymphocytes and synchronizing the timing between uterine receptivity and embryo implantation[4][5]. In the central nervous system, however, the ECS is involved in a specific type of retrograde signaling in which endogenous cannabinoids (endocannabinoids) are released from the post-synaptic neuron and bind to nearby cannabinoid receptor 1 (CB1) -expressing presynapses; this binding elicits a sharp, but temporary, suppression of presynaptic neurotransmitter release.
In this way, the post-synaptic neuron can regulate its own excitability by adjusting synaptic inputs via endocannabinoids that act as retrograde messengers. The endocannabinoid system is thought to be important in long-term potentiation and memory[6][7], motor learning[8], and synaptic plasticity[9].
en.wikipedia.org.
PS Eric, if you the time, the will and a suitably excited endocannabinoid system, could you calculate the key figures of Nokia, YoY, in dolorous dollares??
That is, if no other USA source publishes them in both currencies. |
