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Biotech / Medical : Biotech News
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To: Doc Bones who wrote (6122)5/6/2008 2:57:50 AM
From: idos   of 7143
 
Not an easy task to cover the entire genome. Some regions are very difficult to sequence hence still unknown. People were very enthusiastic about SNPs (the HAP map project) but now we know that Copy Number Variation is responsible for the majority of genetic variation and every new tool take us into further unexplored regions of the genome. In this study, they used fosmid libraries that give better resolution than BAC libraries. However, a few months ago another group used parallel high throughput sequencing to interrogate CNVs and they reached an even higher resolution. So we are getting closer to better understanding of what really makes us so different.
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