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Politics : Politics for Pros- moderated
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To: goldworldnet who wrote (249312)5/9/2008 12:00:01 AM
From: goldworldnet  Read Replies (1) of 793964
 
In vitro production of horse embryos: fundamental aspects

Page 174

Our ability to produce horse embryos in vitro has improved dramatically over the last few years, but much has still to be done. Future studies should focus on why conventional IVF still yields such poor results in the horse. The basic methods successful in other species have failed, and new approaches must therefore take account of unique features of gamete physiology in the equids. This important challenge should endorse this species as an interesting experimental model in which to investigate fundamental aspects of fertilization. Another important hurdle is to unravel what an oocyte requires to become fertilized and capable of supporting embryonic development. Although IVP embryos obtained from IVM oocytes are capable of developing into live offspring, the fact that their developmental competence is low highlights the need to investigate how an oocyte’s nuclear and cytoplasmic entities reorganize to support early embryonic development and how this is affected by culture. To aid this process, current protocols for oocyte and follicle selection could be standardized across laboratories to ensure that comparable data is produced.

igitur-archive.library.uu.nl

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