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Biotech / Medical : Biotech Valuation
CRSP 57.37+0.9%3:59 PM EST

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To: tuck who wrote (26899)5/26/2008 4:15:39 AM
From: Biomaven  Read Replies (2) of 52153
 
But at the end of the day I believe a lot more late-stage drugs have died or been delayed by QTc issues than by animal tox studies.

The only example I can recall off-hand of the 2-year animal studies actually being a gating factor is for Isotechnika's drug, and that was because they changed to an isomer after they had already started their clinical program. I can't recall if those studies are completed or not, but I remember thinking they might be a problem because the comparator cyclosporine is actually somewhat carcinogenic in animal studies.

And while you guys are slaving away over hot keyboards (or whatever), here is where I am:

flickr.com

The elevation in that photo was come by honestly - the shot was taken about half way up a hike to the base of a waterfall and I'm still kind of sore today :)

Having fantastic weather and it's light until nearly midnight - can't imagine what it's like in mid-winter though. Folks living in these valleys might never see the sun for long portions of winter - the mountains on either side seem high enough to prevent the low sun from ever being visible.

Peter
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