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Biotech / Medical : Biotech Valuation

CRSP 57.37

+0.9%

3:59 PM EST

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To: Biomaven who wrote (26900)	5/26/2008 12:10:31 PM
From: tuck	of 52153

>>But at the end of the day I believe a lot more late-stage drugs have died or been delayed by QTc issues than by animal tox studies. << I would guess you're right. Perhaps because a drug developer might see cell proliferation in in vitro studies very early, and quietly kill the compound before anybody hears about it. Whereas QTc signals aren't going to show up until an animal study at the earliest. So perhaps a small -- hard to detect in small samples -- QTc signal is more likely to show up relatively late? So even though you can test for it more quickly, you can't start as soon. This sort of thing is why we have large P3s . . . Anyhow, glad you're enjoying yourself. I'm a little jealous -- I've been landscaping so much that I've hardly climbed, and will likely hike today for the first time this year -- unlike me! This being May, did you sell before you went away? Or merely trust us to hold up the biotechs for you? Cheers, Tuck

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