Version 4
Hi, Please ignore this message. Testing it. Regards, John McCarthy
------------ FDA Approved ------------ Sy3= Synvisc@35% of Retail $-Osteoarthritis-Liquid prosthesis Sy1= Synvisc@100% of Retail $-Osteoarthritis-Liquid prosthesis
----------------- FDA Expected 1997 Hf = Hylaform -Facial Wrinkles-Hylan device -----------------
---------------- NOT FDA APPROVED ---------------- Sold in Canada/Italy Hs = Hylashield -Eye drops -Protect Eyes
==================================== Major Assumption: 1998 USA Revenues from Synvisc ==================================== Annual AHP @ Retail $135,000,000 Annual Price (2 visits) 1,000 BIOX % of AHP .35 BIOX $ Gross Rev $47,250,000
Implied about AHP ==================================== 1998 Patients Treated 135,000
Total Target Patient Population 7,000,000
1998 % Treated 1.93%
Total Osteoarthritis Population 15,600,000 ------------------------------------------------------------------- Biomatrix (BIOX) - 1998 1st 2nd 3rd 4th 1998 =================================================================== Pr Loc Dist ------------------------------------------------------------------- Sy3 USA (AHP) 8,000 10,000 13,000 16,000 47,000 Sy3 NON-USA (AHP) 500 800 1,200 1,600 4,100 Sy3 France (Boe Ing) 400 600 800 1,000 2,800 Sy3 Canada (RPR) 500 500 500 500 2,000 Sy3 Sweden (Roche) 300 300 300 300 1,200 Sy3 Isr./FE (Bayer AG) 300 300 300 300 1,200 Sy3 Italy (Recdati) 150 150 150 150 600 Sy1 England (Biox) 50 100 150 200 500 Sy1 China (Biox) 25 50 75 100 250 Sy1 Norway (Biox) 1 1 1 1 4 Sy1 Finland (Biox) 1 1 1 1 4 Sy1 Switzer (Biox) 1 1 1 1 4 Hf USA (Collagen) 700 900 1,100 1,300 4,000 Hf NON-USA (Collagen) 400 600 800 1,000 2,800 Hs ITAL (Far Farm) 50 50 50 50 200 Other (Biox) 300 300 300 300 1,200 -------------------- ------- ------- ------- ------- ------- Total Product Sales 11,678 14,653 18,728 22,803 67,862 -------------------- ------- ------- ------- ------- ------- Memo:Seq. % N/A 25 28 22 Memo:Yr/Yr % 515 714 N/A N/A -------------------- Milestone Fees -------------------- AHP 1,000 2,000 2,000 2,000 7,000 Boehringer Ingelheim 2,000 2,000 2,000 1,000 7,000 Bayer AG 0 0 1,000 1,000 2,000 -------------------- ------- ------- ------- ------- ------- Total Fees 3,000 4,000 5,000 4,000 16,000 -------------------- ------- ------- ------- ------- ------- Total Net Revenues 14,678 18,653 23,728 26,803 83,862 ================== ====== ======= ======= ======= =======
Product GM (Avg. %) .60 .60 .60 .60 .60 Product GM $ 7,007 8,792 11,237 13,682 40,717 License GM $ 3,000 4,000 5,000 4,000 16,000 -------------------- ------- ------- ------- ------- ------- Total GM $ 10,007 12,792 16,237 17,682 56,717 =================== ======= ======= ======= ======= =======
-------------------- R & D -------------------- Hylagel/Sur.Adhes/Ph1 600 600 600 600 2,400 Hylasine/EarNose/Ph1 600 600 600 600 2,400 Hylasol/Opth Sur/Ph1 200 200 200 200 800 Other 300 300 300 300 1,200 -------------------- ------- ------- ------- ------- ------- Total R&D 1,700 1,700 1,700 1,700 6,800 -------------------- ------- ------- ------- ------- ------- Memo:1997 (est.) 1,400 1,400 1,500 1,600 5,900 -------------------- ------- ------- ------- ------- -------
-------------------- SG&A -------------------- Normal 2,000 2,200 2,400 2,600 9,200 Sy England (Biox) 300 500 600 600 2,000 Sy China (Biox) 300 300 400 500 1,400 -------------------- ------- ------- ------- ------- ------- Total SG&A 2,500 3,000 3,400 3,700 12,600 -------------------- ------- ------- ------- ------- ------- Memo:1997 (est.) 1,400 1,900 2,300 2,600 8,200 -------------------- ------- ------- ------- ------- -------
-------------------- ------- ------- ------- ------- ------- Total R&D/SG&A 4,200 4,700 5,100 5,400 19,400 -------------------- ------- ------- ------- ------- -------
-------------------- ------- ------- ------- ------- ------- Inc. from Operations 5,807 8,092 11,137 12,282 37,317 -------------------- ------- ------- ------- ------- -------
Int.Income- Net (4%) 270 307 358 428 1,364
-------------------- ------- ------- ------- ------- ------- EBT 6,077 8,399 11,495 12,710 38,681 -------------------- ------- ------- ------- ------- -------
Tax Prov. (%) .39 .39 .39 .39 .39 Tax Prov. ($) 2,370 3,276 4,483 4,957 15,086
-------------------- ------- ------- ------- ------- ------- EAT 3,707 5,123 7,012 7,753 23,595 ================== ======= ======= ======= ======= =======
Cash/Mrt.Sec-BOP 27,000 30,707 35,830 42,842 42,842 ================== ======= ======= ======= ======= =======
Shares Outstanding 11,400 11,400 11,400 11,400 11,400 ================== ======= ======= ======= ======= =======
E.P.S .33 .45 .62 .78 2.07 ================== ======= ======= ======= ======= =======
@ PE / Share Price -------------------- ------- ------- ------- ------- ------- 20 41.00 -------------------- ------- ------- ------- ------- ------- 25 52.00 -------------------- ------- ------- ------- ------- ------- 30 62.00 -------------------- ------- ------- ------- ------- ------- 35 72.00 -------------------- ------- ------- ------- ------- ------- 40 82.00 -------------------- ------- ------- ------- ------- ------- 45 93.00 -------------------- ------- ------- ------- ------- ------- 50 103.00 -------------------- ------- ------- ------- ------- -------
Notes: =========================== A.Amendment 5/29/97 to increase auth. shares =========================== TO 60,000,000 FROM 20,000,000. Don't know if ratified.
=========================== B.Ownership at 3/1/97 =========================== Endre A. Balazs 2,161,519 20% Janet I. Denlinger 1,099,085 10% H. Stuart Campbell 61,248 Rory B. Riggs 600,000 6% Others 54,000 Shares Outstanding 6/30/97 11,158,098
=========================== C. Distribution Agreements =========================== Boehringer Ingelheim - 12/18/96 -------------------- Fee:$8.0 million France,Algeria,Morocco Req. Biomedical Specialists:5
-------------------- Wyeth-Ayerst (AHP) - 2/10/97 -------------------- Fee:$25.0 million USA Germany,Austria,Greece,Spain,Portuagal Poland,Hungry,Romania,Bulgaria,Check Turkey,Saudi Arabia,Egypt,Syria,Jordan Req. Biomedical Specialists:Yes(# unknown)
-------------------- Bayer AG - 4/29/97 -------------------- Fee:$5.0 million Israel,Australia,New Zeland,Taiwan,Singapore Indonesia,Thailand,Maylaysia Req. Biomedical Specialists:2 |