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Biotech / Medical : Alexion Pharmaceuticals, Inc. (ALXN)
ALXN 182.500.0%Jul 28 4:00 PM EDT

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From: tnsaf12/8/2008 11:27:19 PM
   of 824
 
Alexion: Blood disorder drug does well in Japan
Monday December 8, 4:24 pm ET
Alexion Pharmaceuticals says blood disorder treatment Soliris does well in Japanese study

CHESHIRE, Conn. (AP) -- Alexion Pharmaceuticals Inc. said Monday a study of its drug Soliris in the treatment of Japanese patients suffering from a rare, life-threatening blood disorder showed several positive results.

Patients saw improvement in kidney function and reductions in the destruction of red blood cells, anemia, transfusion dependence and fatigue, the company said in a statement.

Alexion said the results are similar to those from late-stage studies conducted in the United States and Europe. Regulators have already approved Soliris in both locations to treat the disorder, which is called paroxysmal nocturnal hemoglobinuria.

The disorder, known as PNH, is a chronic disease caused by a mutation in certain adult blood cells. It is normally treated with transfusions and bone marrow transplants.

Soliris is Alexion's only commercial product. The company hopes to launch the drug commercially in Japan in 2010.

Shares of Alexion rose $1.09, or 3.3 percent, to close at $34.37.
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