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Biotech / Medical : Indications -- HIV

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To: DewDiligence_on_SI who wrote (85)2/21/2009 9:13:03 PM
From: Elroy Jetson  Read Replies (1) of 155
 
The concept of "improved compliance" with a single tablet has been much promoted by some pharma firms. Apparently you believe them.

Yet there is no evidence that patients are more likely to take one large tablet, than three smaller ones, once a day.

There is some evidence that compliance is higher with once a day regimens than twice a day regimens. But there's an equal amount of evidence that the downside of a missed dose is greater with a once a day combination than with a twice a day combination.

The improved market share for combination tablets has been bought at the expense of profitability.
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