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Biotech / Medical : GelTex Pharmaceuticals (GELX)

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To: NY0001 who wrote (33)10/25/1997 2:23:00 PM
From: Robert Holmes  Read Replies (2) of 127
 
Cholestagel works by binding bile acid in the intestine, forcing the liver to make more. To manufacture bile acid, the liver requires cholesterol which it gets by extracting it from the blood, thereby reducing a patients cholesterol level.

Rasio, from my understanding, limits the amount of cholesterol that is absorbed from ingested sources. There is a significant population of people whose bodies maintain a naturally high level of cholesterol in the blood even if they control their intake of cholesterol. Rasio would not help these patients.

Lastly, most patients taking statins or other pharmaceuticals require decreases in cholesterol levls that can not be acheived with a product like Rasio. The only figure I've seen for Rasio is somewhere around a 10% reduction. While this would certainly be healthful for the general population, it does not approach the level required for those currently taking statins and bile acid sequestrants. The two classes of products are complimentary, not competitive.
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