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Pastimes : Heart Attacks, Cancer and strokes. Preventative approaches

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From: LindyBill	8/2/2009 7:21:07 PM
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Dr Davis Comment: >>>Re: the homocysteine question. Homocysteine has proven to be among the most complex, unsolved issues facing us. I won't pretend to have the final answer--I don't think anybody has one yet. We do know without question that increased homocysteine yields greater risk for cardiovascular disease. We just don't know if reducing homocysteine with a conventional regimen of B vitamins is an incomplete solution, or wrong altogether, since all the studies showed little or no reduction of cardiovascular risk with folic acid/B6/B12 supplementation. Or, as some others have argued, the folic acid form or B12 forms were the wrong type. The homocysteine issue, I'm afraid, won't be settled any time soon without data to help us understand to how best manage this. In all honesty, what I've been doing--with very little scientific justification--is address homocysteine when it's high, since it often suggests B12 deficiency anyway, and in people with Lp(a), since homocysteine can act as a cofactor in the Lp(a) assembly. My approach is, by no means, the final answer nor terribly insightful. We really need better data on homocysteine.

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