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Biotech / Medical : Ligand (LGND) Breakout!
LGND 197.00+0.2%12:52 PM EST
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To: tommysdad who wrote (10427)10/31/1997 7:17:00 AM
From: Henry Niman  Read Replies (1) of 32384
 
Here's another earlier study suggesting an estrogen indication for Alzheimer's:
Aug. 16, 1996

Estrogen may lower woman's risk of
Alzheimer's

Taking estrogen appears to dramatically reduce a woman's risk of
Alzheimer's disease, the strongest research on the subject so far shows.

"This is the first really good epidemiologic evidence that this treatment
may delay the onset of symptoms for a significant number of years,"
says Zaven Khachaturian of the Alzheimer Association's Ronald and
Nancy Reagan Research Institute. About 4 million Americans have
Alzheimer's.

The study in Friday's Lancet by Richard Mayeux and Gertrude
Sergievsky of Columbia University found that taking estrogen for 10
years after menopause reduced the risk of Alzheimer's by 30% to 40%.

Researchers studied 1,124 women age 70 and up. Of 968 women who
did not take estrogen, 158 developed Alzheimer's. Of 156 who took
estrogen, only nine developed it.

Estrogen users who developed Alzheimer's had symptoms later than
expected.

Experts believe that estrogen aids in the repair and maintenance of
brain cells.

But Neil Buckholtz of the National Institute on Aging says a large
randomized clinical trial will be needed to finally prove estrogen
prevents Alzheimer's.

Estrogen is recommended for relieving menopause symptoms. Studies
show it also reduces the risk of heart disease and slows osteoporosis,
though some studies have linked estrogen with increased risk of breast
cancer. Women should weigh the risks and benefits with their doctor.

By Tim Friend, USA TODAY
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