Biotech Valuation Message Board

STOCKTALK

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor. We ask that you disable ad blocking while on Silicon Investor in the best interests of our community. If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.

Biotech / Medical : Biotech Valuation

CRSP 53.50

-1.3%

3:59 PM EST

Public Reply Prvt Reply Mark as Last Read File

Previous 10 Next 10 Previous Next

To: Ian@SI who wrote (32960)	11/22/2009 6:49:04 PM
From: IRWIN JAMES FRANKEL	2 Recommendations Read Replies (1) of 52153

>>I have repeated to myself 100 times, "Correlation isn't causation". :-) Yep. But the one thing that seems clear (provided the report is correct) is that the MS population has an extremely high rate of stenosis compared to the general population. Could that back-pressure in the "plumbing" lead to an auto-immune malfunction? Maybe. It is worth study. >>But when I combine the P values in your abstract with the anecdotal cures claimed by those having the blockages removed, it certainly raises my hopes that this is a miraculous breakthrough in treating MS. Not for me. The only anecdote that is long enough to offer some reasonable inference of effect is the wife who has had three years without an exacerbation. But with RRMS there are lots of periods of remission and 3 years is not so long as to offer much hope. >> I can even imagine that the iron or other waste product buildup triggers a process or processes which lead directly or indirectly to the myelin attack. I understand that inflammation increases iron in the area as part of the inflammatory response. So MS would increase the iron as an effect not a cause. Feedback loop? No idea. Increasing venal flow: Considering that venal flow is the low pressure side of the "plumbing", wouldn't it be more subject to thrombosis? If so, seems to me that would increase the risks of interventions, including stenting which otherwise would be the obvious first line of attack. Science guys - it is open season on this JD, if I am out in left field again. :-) Can't wait to read the journal articles. ij

Report TOU Violation

Share This Post

Public Reply Prvt Reply Mark as Last Read File

Previous 10 Next 10 Previous Next