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Biotech / Medical : Biotech Valuation
CRSP 55.32+2.7%3:59 PM EST

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To: Ian@SI who wrote (33010)11/27/2009 8:19:30 PM
From: Biomaven2 Recommendations  Read Replies (2) of 52153
 
>>MS and venous strictures

I have an open mind on this. If you take what Zamboni has shown at face value, then there clearly is at least correlation here. If that is independently verified, then we have to establish the direction of causation. There would be three possibilities (in order by my guess as to likelihood:

1. The strictures cause MS, perhaps via some breach of the blood/brain barrier and/or via iron deposition.

2. The MS causes the strictures. This on the face of it seems a little unlikely, but one could imagine some sort of autoimmune reaction in the veins causing inflammation and then strictures.

3. There is some pre-existing condition (genetic or otherwise) that predisposes people to both conditions. That seems the least likely of the three.

So his theory is certainly quite plausible, but like any idea out of left field one needs some independent confirmation. The "treatment" stuff he has done doesn't lend much weight in my view - MS is just too unpredictable to place much weight in basically anecdotal results.

Peter

P.S. "venous" not "venal" - the latter relates to bribery, not veins.
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