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Biotech / Medical : NKTR Drug delivery Company

NKTR 59.32

+2.3%

3:59 PM EST

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From: david nordic	1/12/2010 11:11:30 AM
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UPDATE 1-Nektar posts prelim data from cancer trial Tue Jan 12, 2010 9:47am ESTStocks * Drug shows 32 pct response rate in once-in-14-days dose * Shows 35 pct response rate in once-in-21-days dose * Shares up 5 pct in pre-mkt trade Jan 12 (Reuters) - Nektar Therapeutics (NKTR.O) posted preliminary results from the first stage of a two-stage safety and efficacy trial of its experimental ovarian cancer drug. The company said NKTR-102, which was tested in women with platinum-resistant ovarian cancer, showed an overall response rate of 32 percent in the once-every-14-days dose schedule and 35 percent for the once-every-21-days dose. The response rate was calculated based on certain tumor imaging and/or ovarian cancer biomarker criteria, the company said in a statement. About one-third of the patients in the study remained on NKTR-102 treatment, including a number of patients in the first stage of the study. The overall mid-stage trial has now completed enrollment with a total of 71 patients. The most commonly observed side effects in the study were diarrhea and neutropenia. The drug is also being tested in two other mid-stage clinical trials for patients with metastatic breast cancer and second-line colorectal cancer. Shares of the company were unchanged at $9.53 in morning trade on Nasdaq. (Reporting by Esha Dey in Bangalore; Editing by Anthony Kurian)

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