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Biotech / Medical : RNAi
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From: Ian@SI3/16/2010 3:12:58 PM
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UPDATE 1-Tekmira, Pfizer to collaborate on RNAi delivery system

Thomson Reuters

* To collaborate with Pfizer on RNAi delivery technology

* Tekmira looking to sign more collaborative deals in 2010

* Tekmira shares up 20 pct

March 16 (Reuters) - Canada's Tekmira Pharmaceuticals Corp
said it would collaborate with Pfizer Inc to
evaluate the potential of using its technology to deliver
Pfizer's gene "silencing" mechanism to treat a range of
diseases.

Tekmira's shares shot up 20 percent after it announced the
deal -- its first formal research collaboration with Pfizer.

Tekmira's technology, known as sable nucleic acid-lipid
particle (SNALP), uses lipid nanoparticles to deliver RNAi
therapeutics, such as siRNAs, to the disease site.

"The collaboration combines Tekmira's expertise in the
delivery of RNAi therapeutics with Pfizer's research excellence
in nucleic acid therapeutics," Mark Murray, Tekmira's chief
executive officer said in statement.

Pfizer will evaluate Tekmira's SNALP formulations in
preclinical models. Financial terms of the collaboration were
not disclosed.

"Our goal is to sign additional collaborative agreements in
2010," Murray said.

Shares of Tekmira were trading up 14 Canadian cents at 80
Canadian cents in late morning trade on the Toronto Stock
Exchange. Pfizer's shares were up 5 cents at $17.31 on the New
York Stock Exchange.
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