Indications -- HIV Message Board

STOCKTALK

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor. We ask that you disable ad blocking while on Silicon Investor in the best interests of our community. If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.

Biotech / Medical : Indications -- HIV

Public Reply Prvt Reply Mark as Last Read File

Previous 10 Next 10 Previous Next

To: tuck who wrote (131)	4/11/2010 6:07:15 PM
From: idos	Read Replies (1) of 155

Only compound I've found with dual CCR5/CCR2 antagonist activity in HIV arena is TBR-652, but it was primarily designed as CCR5 antagonist hivandhepatitis.com In addition to the possible inflammatory angle in HIV, CCR2 can act as a co-receptor for HIV. ncbi.nlm.nih.gov Still no idea if Pfizer is going for HIV with their CR5/CCR2 antagonist. The CCR5 antagonist class isn't a big hit to say the least but then, Pfizer is developing a 2nd generation and did try (unsuccessfully) Selzentry for treating RA, so perhaps adding a CCR2 antagonist is something they might try.

Report TOU Violation

Share This Post

Public Reply Prvt Reply Mark as Last Read File

Previous 10 Next 10 Previous Next