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Biotech / Medical : ARIAD Pharmaceuticals
ARIA 23.990.0%Feb 17 4:00 PM EST

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To: Larry Liebman who wrote (189)11/11/1997 2:58:00 AM
From: John Dwyer  Read Replies (2) of 4474
 
Hi all,
Did anybody see the press releases from Cell Genesis a week
or so ago? They demonstrated effective gene delivery and stable
protein production in skeletal muscle tissue for more than six
months using the AAV vector delivery system. They also released
results of their second generation lentivirus vector and showed
long-term, stable expression in liver and muscle tissue.

This is further proof-of-principle of Ariad's regulated gene
therapy approach. Genovo uses several viral (and non-viral) delivery
systems, including AAV, and so it would seem that these results
from CEGE argue that Ariad's program could be quite successful.

John
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