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Biotech / Medical : Geron Corp.

GERN 1.235

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12:08 PM EST

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From: tnsaf	3/28/2011 1:27:48 PM
	1 Recommendation of 3576

Telomere-diabetes link Scientists at The Johns Hopkins University suggest adding age-related diabetes to the list of diseases associated with short telomeres, which already includes cancer and lung disease. Although their insulin-producing beta cells looked healthy, mice with short telomeres had high blood sugar levels and secreted half as much insulin as control mice, according to the study, published recently in PLoS ONE. Closer examination of their beta cells revealed disregulation of p16, a gene linked to aging and diabetes. “This mimics early stages of diabetes in humans where cells have trouble secreting insulin in response to sugar stimulus,” Mary Armanios, a professor of oncology at Johns Hopkins, said in a statement. The results suggest that clinicians might be able to one day measure telomere length to detect diabetes risk, she added. blog.the-scientist.com

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