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Biotech / Medical : Combimatrix (CBMX)
CBMX 6.2500.0%Nov 16 4:00 PM EST

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From: Paul Lee4/11/2011 6:49:52 AM
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CombiMatrix Partners With Clarient to Commercialize CombiMatrix Genomic Profile Tests for Cancer
IRVINE, Calif., April 11, 2011 (GLOBE NEWSWIRE) -- CombiMatrix Corporation (Nasdaq:CBMX - News) announced today that it has entered into a strategic partnership with Clarient, Inc., a GE Healthcare Company, that allows Clarient the right to commercialize the CombiMatrix DNAarray(TM) product portfolio. The DNAarray tests are based on aCGH technology, which provides physicians a comprehensive genomic profile of solid cancer tumors and blood-based cancers, helping to better guide patient treatment decisions.

While conventional test offerings such as cytogenetics, immunohistochemistry (IHC) and fluorescence in-situ hybridization (FISH) are well established in the routine diagnostic work-up for tumors of many cancer patients, array-based genomic testing from CombiMatrix provides a high resolution, genome-wide molecular view of critical DNA copy number changes that cannot be obtained from traditional testing methodologies.

"We are excited about strengthening our relationship with the Clarient team and working together towards increasing clinical acceptance of our DNAarray platform," stated R. Judd Jessup, President and CEO of CombiMatrix. "Clarient's leading position in pathology and oncology is a perfect complement to our leading-edge oncology testing products and services. Our new collaboration calls for cooperative sales and marketing between our companies and also allows for an active relationship between the medical and scientific teams, which over time we believe will help to drive both the commercial adoption of DNAarray testing and the development of new companion diagnostics in the oncology space," concluded Mr. Jessup.

The relationship grants Clarient exclusive rights to commercialize oncology-related tests among commercial laboratories, based on certain minimum levels of sales. The DNAarray tests are utilized for both prognostic and predictive purposes, and can help identify therapeutic targets that are directly associated with FDA-approved chemotherapeutic agents, as well as therapies that are being utilized in large scale biopharmaceutical clinical trials.

This collaboration comes at a time when CombiMatrix is preparing its launch of the DNAarray Oligo 180K Heme Profile, which utilizes content that has been endorsed by the Cancer Cytogenomics Microarray Consortium, the leading authority for the standardization and collaboration amongst array-based platforms in the hematology-oncology diagnostics market. The new platform was designed to query thousands of cancer-specific oncogenes in conjunction with its genome-wide backbone coverage. CombiMatrix believes this new platform provides an important complement to Clarient's extensive molecular diagnostics menu in oncology, and is a direct fit in its continued leadership role in the field of personalized medicine. The collaboration will also allow the companies to engage in further research endeavors and to co-develop reporting tools that will ultimately empower physicians to make more informed treatment decisions for their cancer patients.

About CombiMatrix Corporation

CombiMatrix Corporation, through its wholly owned subsidiary, CombiMatrix Diagnostics, is a CAP/CLIA certified molecular diagnostics laboratory offering comprehensive profiling of chromosomes and genes for both oncology and pre- and postnatal developmental disorders. CombiMatrix Diagnostics offers a comprehensive and proprietary analysis of cancer tumors at the DNA, or molecular level. CombiMatrix was the first commercial clinical laboratory in the United States to make comprehensive DNA-based genomic analysis of solid tumors, including breast, colon, lung, prostate and brain tumors, available to oncology patients and medical professionals. CombiMatrix also offers pre- and postnatal testing services for the detection of abnormalities of genes at the DNA level beyond what can be identified through traditional technologies. Additional information about CombiMatrix Corporation is available at www.combimatrix.com. Additional information about CMDX is available at www.cmdiagnostics.com or by calling 1-800-710-0624.
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