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From: ~digs	4/12/2011 10:51:42 PM
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KBLB.pk + SIAL Sigma-Aldrich to make modified silk worms finance.yahoo.com A Sigma-Aldrich unit has signed an agreement with Kraig Biocraft Laboratories Inc. to develop genetically modified silkworms for the production of spider silk. The transfer of silk genes from the spider to the silkworm is expected to allow the mass production of silk with enhanced strength and elasticity with potential textiles and biomedical applications, such as sutures, tendon and ligament repair, bulletproof vests and automobile airbags, said Sigma Life Science, the biological products and services research business of Sigma-Aldrich. Last year, Kraig Biocraft Laboratories produced hybrid silkworms with randomly inserted spider silk genes, yielding hybrid spider silkworm silk with greater strength and durability than native silkworm silk. Sigma-Aldrich said it would build on this research by using its technology to insert spider silk genes into the silkworm genome while removing endogenous silkworm silk genes. The resulting transgenic silkworm is expected to be capable of spinning pure spider silk at commercially viable production levels, Sigma-Aldrich said.

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